Brynne is an Assistant Professor (Ad Astra Fellow) in the School of Nursing, Midwifery & Health Systems and an MSCA Fellow. Her research focuses on using theory driven evaluation methodology to understand and improve health systems, specifically at the community level in low- and middle-income countries. Within this, Brynne is exploring the use of realist evaluation methodology for health policy and systems research in various contexts. Most of her previous work involves research partnerships with NGO's in sub-Saharan Africa using operations research/implementation science to support strengthening health interventions. She has research experience in Uganda, Tanzania, Kenya, Sierra Leone, Lebanon, Turkey and Ireland.

Brynne recently completed her Marie Skłodowska-Curie Actions (MSCA) and Irish Research Council CoFund individual post-doctoral fellowship under the CAROLINE scheme, in partnership with Concern Worldwide in Kenya, where she conducted a realist evaluation of a community engagement for health intervention in Northern Kenya. She co-founded the Irish Realist Researcher Support Group, and is a Board member of the Irish Forum for Global Health.